Genomic Profiling of the Overlap Phenotype between Psoriasis and Atopic Dermatitis

The study investigates the genomic profiling of patients with psoriasis, atopic dermatitis (AD), and an overlap phenotype between the two conditions. It finds that the overlap phenotype exhibits molecular features predominantly associated with psoriasis, suggesting that genomic biomarkers can effectively differentiate between psoriasis and AD at the molecular level.

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Good practice intervention for clinical assessment and diagnosis of atopic dermatitis: Findings from the atopic dermatitis quality of care initiative

The Atopic Dermatitis Quality of Care Initiative was launched to address the misdiagnosis and undertreatment of atopic dermatitis (AD) by identifying barriers to care and promoting good practice interventions. Key findings highlighted the importance of using validated diagnostic criteria, established scoring tools, and fostering communication among healthcare providers and patients to improve clinical assessment and diagnosis of AD.

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The translational revolution in atopic dermatitis: the paradigm shift from pathogenesis to treatment

The research discusses the shift in understanding atopic dermatitis (AD) from its pathogenesis to treatment, emphasizing the need for personalized approaches due to the condition’s complexity and heterogeneity. Recent advancements in identifying biomarkers and immune pathways are driving a translational revolution in AD therapies, aiming for targeted treatments based on individual patient characteristics.

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Quality of Life and Burden of Moderate-to-Severe Atopic Dermatitis in Adult Patients Within the Asia–Pacific Region: A Cross-sectional Survey

This cross-sectional study highlights the significant impact of moderate-to-severe atopic dermatitis (AD) on quality of life and economic burden among adult patients in the Asia-Pacific region. The findings reveal substantial impairment in quality of life, with high levels of pain, discomfort, and anxiety reported, alongside considerable annual costs associated with the condition. The study emphasizes the need for proactive management of AD and its comorbidities to alleviate this burden.

Quality of Life and Burden of Moderate-to-Severe Atopic Dermatitis in Adult Patients Within the Asia–Pacific Region: A Cross-sectional Survey Read More »

Bridging the Gap: Comparing Patient-Clinician Views on Treatment Goals and Communication in the Management of Atopic Dermatitis Within the Asia–Pacific Region

This study compares the perspectives of patients with atopic dermatitis and dermatologists in the Asia-Pacific region regarding treatment goals and communication. While both groups largely agree on treatment objectives, patients prioritize prevention of exacerbations and minimizing side effects more than dermatologists, and a notable percentage of patients expressed dissatisfaction with communication despite overall satisfaction with treatment. The findings highlight areas for improvement in patient-centered care.

Bridging the Gap: Comparing Patient-Clinician Views on Treatment Goals and Communication in the Management of Atopic Dermatitis Within the Asia–Pacific Region Read More »

Using Automated Machine Learning to Predict Necessary Upcoming Therapy Changes in Patients With Psoriasis Vulgaris and Psoriatic Arthritis and Uncover New Influences on Disease Progression: Retrospective Study

This study aims to develop highly accurate machine learning models using automated machine learning (AutoML) to predict necessary therapy changes and identify factors influencing disease progression in patients with psoriasis vulgaris and psoriatic arthritis. The results indicate that specific patient features, such as initial therapeutic agents and quality of life changes, significantly impact treatment decisions and disease outcomes, ultimately enhancing clinical decision-making for improved patient care.

Using Automated Machine Learning to Predict Necessary Upcoming Therapy Changes in Patients With Psoriasis Vulgaris and Psoriatic Arthritis and Uncover New Influences on Disease Progression: Retrospective Study Read More »

A Multidisciplinary Approach Is Beneficial in Atopic Dermatitis

The research emphasizes the benefits of a multidisciplinary approach in managing atopic dermatitis (AD), a chronic inflammatory skin disorder that significantly impacts patients’ quality of life. By accurately assessing individual risk profiles and enhancing patient-physician decision-making, this approach aims to improve treatment outcomes and overall care for patients with moderate-to-severe AD. The review calls for more data to establish standardized patient profiles and strategies for effective AD management.

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Ustekinumab: In Psoriasis and Beyond —A Derm atological Perspective

Ustekinumab is an interleukin 12/23 inhibitor approved for moderate-to-severe plaque psoriasis and psoriatic arthropathy, and this review highlights its dermatological implications and applications. The findings indicate that ustekinumab is effective not only for psoriasis but also for various other dermatological conditions, including hidradenitis suppurativa and alopecia areata, and is particularly beneficial for childhood psoriasis and adult patients with concurrent Crohn’s disease.

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Severe atopic dermatitis in early infancy: characteristics, challenges and new perspectives in clinical practice

This research paper discusses the prevalence and challenges of severe atopic dermatitis in infants, emphasizing the need for age-specific management and early identification for potential prevention of comorbidities. It also highlights the importance of distinguishing between severe AD and immunodeficiency. The paper provides recommendations for systemic treatment and updates on general management.

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